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Echinacoside
go.drugbank.com/drugs/DB15488Investigational[A184577] Echinacoside has demonstrated inhibition of apoptosis in neural cell lines, demonstrating potential for use in the treatment of neurological conditions.[A184592]
Esmirtazapine
go.drugbank.com/drugs/DB06678InvestigationalMerck has terminated its internal clinical development program for esmirtazapine as of March 2010. … Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause.
Brasofensine
go.drugbank.com/drugs/DB04857ExperimentalIn November 2001, NeuroSearch confirmed that the drug's development was discontinued in favor of NS 2230.
Alfaxalone
go.drugbank.com/drugs/DB11371ExperimentalVet approvedAlfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. … Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin.
Hydroxystilbamidine
go.drugbank.com/drugs/DB14753ApprovedHydroxystilbamidine isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. Hydroxystilbamidine ...
NS-2359
go.drugbank.com/drugs/DB05805InvestigationalEnhancing the function of the three neurotransmitters serotonin, noradrenalin and dopamine, NS2359 has a desired "triple-mode-of-action".
AZD3409
go.drugbank.com/drugs/DB04893ExperimentalPhase I trials were initiated January 2003, and were ongoing as of February 2004. As of February 2007 the development of AZD3409 had been discontinued.
Linopristin
go.drugbank.com/drugs/DB19296ExperimentalIt is one part of the combination product NXL 103, along with [Virginiamycin M1]. … The combination product was under investigation in clinical trials NCT00653172 and NCT00949130 for treatment of various bacterial infections.
Rintodestrant
go.drugbank.com/drugs/DB21472InvestigationalRintodestrant has a monoisotopic molecular weight of 462.09 Da. … Rintodestrant is under investigation in clinical trial NCT03455270 (G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer).