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Flurbiprofen axetil
go.drugbank.com/drugs/DB14938InvestigationalFlurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
Dihydromyricetin
go.drugbank.com/drugs/DB15645InvestigationalDihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).
Pirepemat
go.drugbank.com/drugs/DB19165InvestigationalPirepemat is under investigation in clinical trial NCT05258071 (A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD)).
Aminobenzoic acid
go.drugbank.com/drugs/DB02362ApprovedWithdrawnIt used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Desmoteplase
go.drugbank.com/drugs/DB04925InvestigationalWhen a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. … Desmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots.
ARG201
go.drugbank.com/drugs/DB06621ExperimentalThis drug was investigated in the completed clinical trial NCT0000567 (Multicenter Phase II Trial of Oral Type I Bovine Collagen in Scleroderma) … ARG201, a bovine-derived Type I collagen, aims to induce immune tolerance in patients with Diffuse Systemic Scleroderma (dcSSc).
MUC1 Dendritic Cell Vaccine
go.drugbank.com/drugs/DB05477InvestigationalThe Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign antigens to the T-cells to initiate a primary response in the effector arm of the immune system … These cells are then given back to a patient as a vaccine in order to allow for a potent immune response to cancer.
JNJ-54175446
go.drugbank.com/drugs/DB15358InvestigationalJNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid
Turofexorate isopropyl
go.drugbank.com/drugs/DB12719InvestigationalFxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
GFT14
go.drugbank.com/drugs/DB05061ExperimentalGFT14 is destined to improve the condition of patients at risk from cardiovascular disease by a simultaneous and favorable action on the plasmatic lipids (rise of HDL- cholesterol et lowering of triglycerides … ) and on other risk factors such as hypertension or diabetes.