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Displaying results 4941 - 4950 of 10000 in total
  1. Drug

    GDC-0927

    go.drugbank.com/drugs/DB14934
    Investigational

    GDC-0927 is under investigation in clinical trial NCT02316509 (A Study of GDC-0927 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer).

  2. Drug

    MK-8666

    go.drugbank.com/drugs/DB14937
    Investigational

    MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).

  3. Drug

    Florbenazine F-18

    go.drugbank.com/drugs/DB14945
    Investigational

    Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Florbenazine f 18, Florbenazine F-18
  4. Drug

    AZD-7687

    go.drugbank.com/drugs/DB14949
    Investigational

    AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study).

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Margetuximab

    go.drugbank.com/drugs/DB14967
    ApprovedInvestigational

    The HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). … Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by _ERBB2_ overexpression, a higher grade, a more aggressive phenotype, and a worse prognosis compared to HER2-negative

    Categories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors, HER2 Receptor Antagonists
  6. Drug

    Bacillus calmette-guerin substrain tokyo 172-1 live antigen

    go.drugbank.com/drugs/DB14968
    Investigational

    Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial NCT03091660 (S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive

    Synonyms: Bacillus calmette-guerin substrain tokyo 172-1 live antigen
  7. Drug

    Alobresib

    go.drugbank.com/drugs/DB14970
    Investigational

    Alobresib is under investigation in clinical trial NCT02607228 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants

  8. Drug

    INVAC-1

    go.drugbank.com/drugs/DB16196
    Investigational

    INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

    Synonyms: Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse transcriptase (htert) fusion protein, Human telomerase reverse transcriptase (htert) dna vaccine invac-1
  9. Drug

    IONIS-FGFR4Rx

    go.drugbank.com/drugs/DB16198
    Investigational

    IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients).

  10. Drug

    Ispronicline

    go.drugbank.com/drugs/DB16205
    Investigational

    Ispronicline is under investigation in clinical trial NCT00109564 (A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)).

    Categories: Heterocyclic Compounds, 1-Ring