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Clinafloxacin
go.drugbank.com/drugs/DB14025ExperimentalIt has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.
Exbivirumab
go.drugbank.com/drugs/DB17747ExperimentalIt is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202]
Cyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalCyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. … Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Cenacitinib
go.drugbank.com/drugs/DB21735InvestigationalThe usage of the INN stem '-citinib' in the name indicates that Cenacitinib is a Janus kinase inhibitor. … Cenacitinib is under investigation in clinical trial NCT05688852 (VTX958 for the Treatment of Moderately to Severely Active Crohn's Disease).
Protocatechualdehyde
go.drugbank.com/drugs/DB11268ApprovedAlso known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza … Protocatechualdehyde possesses antiproliferative and pro-apoptotic properties against human breast cancer cells and colorectal cancer cells by reducing the expression of pro-oncogenes β-catenin and cyclin
Trenbolone
go.drugbank.com/drugs/DB11551ExperimentalVet approvedPlasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. … Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite.
Altretamine
go.drugbank.com/drugs/DB00488ApprovedWithdrawnAn alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Tunicamycin
go.drugbank.com/drugs/DB13172ExperimentalOne member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first … Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
go.drugbank.com/drugs/DB06942ExperimentalThis compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.