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Displaying results 4941 - 4950 of 10000 in total
  1. Drug

    Propiverine

    go.drugbank.com/drugs/DB12278
    Approved

    Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) [A32576]. … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents [L2327], [L2328].

    Categories: Adrenergic alpha-1 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: MÄ°CTONORM 5 MG KAPLI TABLET, 98 ADET
  2. Drug

    Radotinib

    go.drugbank.com/drugs/DB12323
    Investigational

    Radotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Ricolinostat

    go.drugbank.com/drugs/DB12376
    Investigational

    Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Relebactam

    go.drugbank.com/drugs/DB12377
    ApprovedInvestigational

    [A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. … Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam].

    Categories: MATE 1 Substrates, MATE 2 Substrates
  5. Drug

    Anagliptin

    go.drugbank.com/drugs/DB12417
    Investigational

    Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    HSD-016

    go.drugbank.com/drugs/DB12419
    Investigational

    Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Muplestim

    go.drugbank.com/drugs/DB12431
    Investigational

    Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL … -3) in HIV Infected Patients With Cytopenia).

    Categories: Interleukin-3Synonyms: Interleukin 3, Interleukin-3
  8. Drug

    Lynestrenol

    go.drugbank.com/drugs/DB12474
    ApprovedWithdrawn

    Lynestrenol is a progestin and prodrug of [norethisterone].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRÄ°L 5 MG TABLET, 30 ADET
  9. Drug

    Copanlisib

    go.drugbank.com/drugs/DB12483
    ApprovedInvestigational

    Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. … PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE-5-CARBOXAMIDE, 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE-5-CARBOXAMIDE
  10. Drug

    Pimonidazole

    go.drugbank.com/drugs/DB12485
    Investigational

    Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.

    Categories: Heterocyclic Compounds, 1-Ring