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Bethanidine
go.drugbank.com/drugs/DB00217ApprovedA guanidinium antihypertensive agent that acts by blocking adrenergic transmission.
Ancriviroc
go.drugbank.com/drugs/DB19773ExperimentalAncriviroc has a monoisotopic molecular weight of 556.2 Da. … Ancriviroc is a small molecule drug. The usage of the INN stem '-viroc' in the name indicates that Ancriviroc is a CCR5 (Chemokine CC motif receptor 5) receptor antagonist.
Xemilofiban
go.drugbank.com/drugs/DB21058ExperimentalXemilofiban has a monoisotopic molecular weight of 358.16 Da. … Xemilofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Xemilofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Amdizalisib
go.drugbank.com/drugs/DB21514InvestigationalAmdizalisib has a monoisotopic molecular weight of 390.11 Da. … Amdizalisib is a small molecule drug.
Inaxaplin
go.drugbank.com/drugs/DB21521InvestigationalInaxaplin has a monoisotopic molecular weight of 417.13 Da. … Inaxaplin is a small molecule drug.
Imdatifan
go.drugbank.com/drugs/DB21643ExperimentalImdatifan has a monoisotopic molecular weight of 385.05 Da. … Imdatifan is a small molecule drug. The usage of the INN stem '-tifan' in the name indicates that Imdatifan is a hypoxia inducible factor (HIF)-2alpha (HIF-2a) inhibitor.
Fosdenopterin
go.drugbank.com/drugs/DB16628Approved[A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity. … In 2009 a recombinant, E. coli-produced cPMP was granted orphan drug designation by the FDA, becoming the first therapeutic option for patients with MoCD type A.
Selexipag
go.drugbank.com/drugs/DB11362ApprovedInvestigationalPAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes. … Marketed by Actelion Pharmaceuticals under brand name Uptravi, selexipag and its active metabolite, ACT-333679 (MRE-269), act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary
Phenindamine
go.drugbank.com/drugs/DB01619ApprovedPhenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. … Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells.