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Displaying results 4951 - 4960 of 10000 in total
  1. Drug

    Natural Killer Cell

    go.drugbank.com/drugs/DB15721
    Investigational

    These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral blood. … Generally, the number of NK cells collected in the peripheral blood mononuclear cell (PBMC) is too low for sufficient potency, and ex vivo expansion is performed.

  2. Drug

    Deudextromethorphan

    go.drugbank.com/drugs/DB19054
    Investigational

    Deudextromethorphan is under investigation in clinical trial NCT02153502 (Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an

  3. Drug

    beta-Hydroxybutyric acid

    go.drugbank.com/drugs/DB16506
    Investigational

    Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236

  4. Drug

    Galidesivir

    go.drugbank.com/drugs/DB11676
    Investigational

    [A191451] In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses. … Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus.

  5. Drug

    Fenspiride

    go.drugbank.com/drugs/DB08979
    Investigational

    Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. … It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis

  6. Drug

    Ethyl pyruvate

    go.drugbank.com/drugs/DB05869
    Investigational

    CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.

  7. Drug

    Venglustat

    go.drugbank.com/drugs/DB14966
    Investigational

    Venglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men).

  8. Drug

    Mestranol

    go.drugbank.com/drugs/DB01357
    ApprovedWithdrawn

    The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.

    Mixtures: LUTORAL-E
  9. Drug

    Doxofylline

    go.drugbank.com/drugs/DB09273
    Investigational

    Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169]. … As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies.

  10. Drug

    Formebolone

    go.drugbank.com/drugs/DB01569
    IllicitInvestigational

    Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. … It has been used experimentally in the treatment of growth retardation, and has been noted to increase bone mass.