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Romlusevimab
go.drugbank.com/drugs/DB16494InvestigationalRomlusevimab (BRII-198) was under investigation in clinical trials (NCT04479644 and NCT04691180) to treat COVID-19, focusing on its safety, tolerability, and pharmacokinetics.
Categories: Amino Acids, Peptides, and ProteinsTopiroxostat
go.drugbank.com/drugs/DB01685InvestigationalTopiroxostat and its metabolites are shown to be unaffected by renal complications, thus may be effective in patients with chronic kidney diseases [A19657]. … Approved for therapeutic use in Japan since 2013, topiroxostat is marketed under the name Topiloric and Uriadec and is orally administered twice daily.
M0002
go.drugbank.com/drugs/DB05091InvestigationalM0002 is an orally-active selective vasopressin antagonist that inhibits water re-absorption from the kidneys. … It is a vasopressin 2 antagonist and represents a new class of compounds – aquaretics – that produce profound diuresis without loss of electrolytes.
SR-123781A
go.drugbank.com/drugs/DB05361InvestigationalSR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Categories: Heparin and similarsXTL-001
go.drugbank.com/drugs/DB05405InvestigationalXTL001 is an investigational monoclonal antibody (MAb) product developed by XTL Biopharmaceuticals to evaluate the safety profile and antiviral activity of the compound in patients chronically infected
Categories: Amino Acids, Peptides, and ProteinsFlorbetapir F-18
go.drugbank.com/drugs/DB09149ApprovedInvestigationalwho are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline. … that plays a key role in Alzheimer's Disease pathogenesis.
Synonyms: 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylanilineFluprednidene acetate
go.drugbank.com/drugs/DB14634InvestigationalFluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties.
Mixtures: Vobaderm 1mg/g + 20mg/g CremeCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsEquine Botulinum Neurotoxin A Immune FAB2
go.drugbank.com/drugs/DB13900ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in adults and pediatric patients. … Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A.
Nabiximols
go.drugbank.com/drugs/DB14011InvestigationalSativex® is available in a 1:1 formulation of THC:CBD as an oro-mucosal pump spray used for treatment of neuropathic pain from Multiple Sclerosis (MS) and for intractable cancer pain. … adequately to other therapy and who demonstrate meaningful improvement during an initial trial of therapy.
Categories: Cannabinoids and similarsBentoquatam
go.drugbank.com/drugs/DB00516ApprovedBentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin. … Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak.