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Displaying results 4971 - 4980 of 10000 in total
  1. Drug

    Nirmatrelvir

    go.drugbank.com/drugs/DB16691
    ApprovedInvestigational

    [L33354] 3CL<sup>PRO</sup> is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. … Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CL<sup>PRO</sup>) inhibitor that is the subject of clinical trial NCT04756531.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    Durlobactam

    go.drugbank.com/drugs/DB16704
    ApprovedInvestigational

    Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases. … [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of _Acinetobacter baumannii-calcoaceticus_

    Synonyms: (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE, SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER
  3. Drug

    Azasetron

    go.drugbank.com/drugs/DB16837
    Investigational

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  4. Drug

    Naringin

    go.drugbank.com/drugs/DB16859
    Experimental

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  5. Drug

    ATH434

    go.drugbank.com/drugs/DB16965
    ApprovedInvestigational

    Synonyms: 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-oneCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Enadoline

    go.drugbank.com/drugs/DB16967
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Pelabresib

    go.drugbank.com/drugs/DB17129
    Investigational

    Synonyms: 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-isoxazolo(5,4-d)(2)benzazepin-4-yl)acetamide, 4h-isoxazolo(5,4-d)(2)benzazepine-4-acetamide, 6-(4-chlorophenyl)-1-methyl-, (4s)Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Bromopyruvate

    go.drugbank.com/drugs/DB17135
    Experimental

    Synonyms: 3-bromo-2-oxopropanoic acid, 3-bromopyruvateCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    (R)-Gossypol

    go.drugbank.com/drugs/DB17379
    Investigational

    (R)-Gossypol is the R-isomer of [Gossypol].

    Synonyms: (r)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene), (R)-Gossypol
  10. Drug

    Vamifeport

    go.drugbank.com/drugs/DB17692
    Investigational

    Vamifeport is being investigated for the treatment of beta-thalassemia.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2-(2-((2-(1h-benzimidazol-2-yl)ethyl)amino)ethyl)-n-((3-fluoropyridin-2-yl)methyl)-1,3-oxazole-4-carboxamide, 4-oxazolecarboxamide, 2-(2-((2-(1h-benzimidazol-2-yl)ethyl)amino)ethyl)-n-((3-fluoro-2-pyridinyl)methyl)-