Bromopyruvate

DB17135ExperimentalSmall molecule

Bromopyruvate: Overview.

Mechanism: Pharmacologically active on Glyceraldehyde-3-phosphate dehydrogenase, Histone deacetylase 1, and Histone deacetylase 3
Curator reviewed
Formula / weight: C₃H₃BrO₃ · 166.958 g/mol (avg)
Also known as: 3-bromo-2-oxopropanoic acid · 3-bromopyruvate · 3-bromopyruvic acid · Bromopyruvic acid · β-Bromopyruvic acid
Code names: NSC-11731 · NSC-62343

Resolves to

Compound

UNII63JMV04GRKCAS1113-59-3ChEMBLCHEMBL177837ChEBI95046

Structure

InChIKeyPRRZDZJYSJLDBS-UHFFFAOYSA-NSMILESOC(=O)C(=O)CBr

Targets

P04406GAPDHQ13547HDAC1O15379HDAC3P52789HK2

Transporters

P53985SLC16A1Q8N695SLC5A8

What you can answer from here — as of September 13, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bromopyruvate, and which of those have an active Phase 3 trial?

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