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Displaying results 4971 - 4980 of 10000 in total
  1. Drug

    Telitacicept

    go.drugbank.com/drugs/DB18312
    Investigational

    Synonyms: (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF13B) HUMAN EXTRACELLULAR DOMAIN FRAGMENT (13-118)-PEPTIDE, (1-106) FUSION PROTEIN WITH HUMAN IMMUNOGLOBULIN G1
  2. Drug

    Papaverine

    go.drugbank.com/drugs/DB01113
    ApprovedInvestigational

    It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. … The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.

    Categories: Heterocyclic Compounds, 2-Ring, Drugs Used in Erectile DysfunctionProducts: PAPAVERİN HCL GALEN 50 MG/2 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL, PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 10 ADET
  3. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … As a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety profile [A31745]. Mifamurtide is marketed in Europe as Mepact for intravenous infusion.

    Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET, MEPACT® POLVO PARA CONCENTRADO PARA DISPERSIÓN PARA PERFUSIÓN
  4. Drug

    Nifuroxazide

    go.drugbank.com/drugs/DB13855
    Investigational

    Mixtures: METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSION, METRONIDAZOL/NIFUROXAZIDA 300 MG/100 MG.Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Edotreotide yttrium Y-90

    go.drugbank.com/drugs/DB17160
    Investigational

    Synonyms: Yttrium Y-90 n-((4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl)-d-phe-cys-tyr-d-trp-lys-thr-cys-thr (2-7)disulfide, Y-90 dota-tyr(3)-octreotide
  6. Drug

    Dazukibart

    go.drugbank.com/drugs/DB18429
    Investigational

    Synonyms: Immunoglobulin G1 [236-alanine,237-alanine,239-alanine,de-C-terminal-lysine], anti-(human interferon β) (human-Mus musculus monoclonal PF-06823859 γ1-chain), disulfide with human-Mus musculus monoclonal, Recombinant humanized monoclonal antibody (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) directed against human soluble cytokine interferon beta.
  7. Drug

    Brentuximab vedotin

    go.drugbank.com/drugs/DB08870
    ApprovedInvestigational

    Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). … In January 2012, the drug label was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and death due to opportunistic JC virus infection post-treatment.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET, ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION)
  8. Target

    Intracellular exo-alpha-(1->5)-L-arabinofuranosidase

    go.drugbank.com/bio_entities/BE0001766
    TargetGeobacillus stearothermophilus

    Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans).

    Polypeptides: Intracellular exo-alpha-(1->5)-L-arabinofuranosidaseSynonyms: Intracellular arabinan exo-alpha-(1->5)-L-arabinosidase
  9. Drug

    Siltuximab

    go.drugbank.com/drugs/DB09036
    ApprovedInvestigational

    It is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology.

    Categories: Interleukin-6 Antagonist, Cytochrome P-450 CYP3A InducersProducts: SYLVANT 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET, SYLVANT 400 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET
  10. Target

    5-oxoprolinase

    go.drugbank.com/bio_entities/BE0002268
    TargetEnzymeHumans

    Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate

    Polypeptides: 5-oxoprolinaseSynonyms: 5-OPase, 5-oxo-L-prolinase