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Displaying results 4981 - 4990 of 8974 in total
  1. Drug

    Flurothyl

    go.drugbank.com/drugs/DB08969
    ApprovedWithdrawn

    It was formerly used to induce convulsions as a alternative to electroshock therapy.

  2. Drug

    Efonidipine

    go.drugbank.com/drugs/DB09235
    Investigational

    The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis and acute renal failure [A32001]. … Efonidipine is a calcium channel blocker of the _dihydropyridine class_, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, _Landel_.

  3. Drug

    Molsidomine

    go.drugbank.com/drugs/DB09282
    ApprovedWithdrawn

    Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones.

  4. Drug

    Larazotide

    go.drugbank.com/drugs/DB05645
    Investigational

    An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.

  5. Drug

    Rifabutin

    go.drugbank.com/drugs/DB00615
    ApprovedInvestigational

    A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.

    Categories: Antiinfectives for Systemic Use, Drugs for Acid Related Disorders
  6. Drug

    Elsubrutinib

    go.drugbank.com/drugs/DB18850
    Investigational

    With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State). … Elsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants

  7. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

  8. Drug

    Cytisine

    go.drugbank.com/drugs/DB09028
    Investigational

    Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost. … Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy.

  9. Drug

    NOV-002

    go.drugbank.com/drugs/DB05393
    Investigational

    It has been administered to over 10,000 patients, demonstrating clinical efficacy and excellent safety data. … NOV-002 is approved and marketed in the Russian Fereration by Pharma BAM under the trade name Glutoxim.

  10. Drug

    Xylazine

    go.drugbank.com/drugs/DB11477
    InvestigationalVet approved

    [L42680] The intentional and unintentional use of xylazine is a cause for concern due to its side effects. … [A32545] Xylazine is not approved for human use and requires a veterinary licence for its purchase and use.