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Displaying results 41 - 50 of 144648 in total
  1. Drug

    Zopapogene imadenovec

    go.drugbank.com/drugs/DB24672
    ApprovedInvestigational

    [L54071] It is the first and only therapy approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with RRP, receiving full FDA approval on August 15, 2025.[L54081] … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory

    Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, Replication-deficient gorilla adenovirus vector (strain GC46) encoding human papillomavirus (HPV) type 6 and type 11 antigens comprising 11 epitopes derived from regions of the E2, E4, E6, and E7 proteins
  2. Drug

    Atacicept

    go.drugbank.com/drugs/DB06399
    ApprovedInvestigational

    [L63797] Reducing BAFF- and APRIL-mediated signaling lowers production of galactose-deficient IgA1, an aberrant antibody whose deposition in the kidney drives IgA nephropathy. … factor (BAFF) and A Proliferation Inducing Ligand (APRIL).

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein (Fc5)
  3. Drug

    Zenocutuzumab

    go.drugbank.com/drugs/DB15559
    ApprovedInvestigational

    Zenocutuzumab is a low-fucose humanized full-length immunoglobulin G1 (IgG1) bispecific HER2- and HER3-directed bispecific antibody. … [L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and her3 receptors.), Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer
  4. Drug

    Pisum sativum whole

    go.drugbank.com/drugs/DB15545
    Approved

    Pisum sativum whole allergenic extract is used in allergenic testing.

    Synonyms: Pisum album whole, Garden pea whole
  5. Drug

    Mucor circinelloides f. lusitanicus

    go.drugbank.com/drugs/DB15525
    Approved

    Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, mucor circinelloides f. lusitanicus, Mucor circinelloides f. lusitanicus whole
  6. Drug

    Salix nigra bark

    go.drugbank.com/drugs/DB14169
    ApprovedWithdrawn

    Salix nigra bark allergenic extract is used in allergenic testing.

    Synonyms: Black willow bark, Salix dubia bark
  7. Drug

    Moringa oleifera leaf

    go.drugbank.com/drugs/DB14362
    Investigational

    Moringa oleifera leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Maranga Leaf, Shigru Leaf
  8. Drug

    Turnera diffusa leaf

    go.drugbank.com/drugs/DB14302
    Investigational

    Turnera diffusa leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Damiana Leaf, Turnera diffusa leaf
  9. Drug

    Frangula purshiana bark

    go.drugbank.com/drugs/DB15478
    Approved

    Synonyms: Bearberry bark, Chittem barkMixtures: Mucinum (cascara and Senna Tablets)
  10. Drug

    Chamaecyparis obtusa leaf

    go.drugbank.com/drugs/DB14686
    Investigational

    Synonyms: Hinoki leaf, Hinoki cypress leaf