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Displaying results 41 - 50 of 14509 in total
  1. Drug

    2-O, 3-O desulfated heparin

    go.drugbank.com/drugs/DB17569
    Investigational

    Synonyms: 2-O, 3-O desulfated heparin
  2. Drug

    Nedaplatin

    go.drugbank.com/drugs/DB13145
    ApprovedInvestigational

    Nedaplatin is a second generation platinum analog [A20300]. It is less nephrotoxic than [DB00515] but has proven equally effective. It was approved for use in Japan in 1995.

    Synonyms: (glycolato-O,O')diammineplatinum(II)Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  3. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.

    Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansSynonyms: Human t-PA (residues 1-3 and 176-527)
  4. Drug

    6-O-benzylguanine

    go.drugbank.com/drugs/DB11919
    Investigational

    6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others

    Synonyms: O(6)-Benzylguanine, O6-benzylguanineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    4-O-Demethylpenclomedine

    go.drugbank.com/drugs/DB06331
    Experimental

    Synonyms: 4-Dmpen, 4-Dm-penCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    O-Benzylsulfonyl-Serine

    go.drugbank.com/drugs/DB01973
    Experimental

    Synonyms: O-Benzylsulfonyl-Serine
  7. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Synonyms: 2-(Propylamino)-o-propionotoluidide, o-Methyl-2-propylaminopropionanilideMixtures: Dentsply 4% Prilocaine and Epinephrine Injection 1:200,000, Lidocaine and Prilocaine Lidocaine and Prilocaine
  8. Drug

    Colestipol

    go.drugbank.com/drugs/DB00375
    Approved

    [FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane
  9. Drug

    1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose

    go.drugbank.com/drugs/DB01920
    Experimental

    Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem]

    Synonyms: 1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose
  10. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].

    Synonyms: 1-(o-Chlorotrityl)imidazole, 1-(o-Chloro-α,α-diphenylbenzyl)imidazoleMixtures: Mecort C (Clotrimazole and Hydrocortisone Acetate Cream), Clotrimazole and Betamethasone Dipropionate