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Butabarbital
go.drugbank.com/drugs/DB00237ApprovedIllicitWithdrawn[A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital].[A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.[L13613] … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.
Synonyms: 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-sec-butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrioneInternational brands: Sarisol No. 2Aminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Synonyms: 5-ALA, 5-Aminolevulinic acidProducts: GLIOLAN, POWDER FOR ORAL SOLUTION, 30 MG/ML, Alacare 8 mg wirkstoffhaltiges PflasterSulfisoxazole
go.drugbank.com/drugs/DB00263ApprovedVet approvedA short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-Dimethyl-5-sulfanilamidoisoxazole, 3,4-Dimethyl-5-sulfonamidoisoxazoleAdenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Synonyms: 5'-AMP, Adenosine-5'PInternational brands: My-B-DenMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation
Synonyms: 5-ASA, m-Aminosalicylic acidProducts: VERALAZİN 4 G/100 ML REKTAL SÜSPANSİYON, 7 ADET, 5-asaFlavin adenine dinucleotide
go.drugbank.com/drugs/DB03147ApprovedA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase.
Categories: Heterocyclic Compounds, 3-Ring, Vitamin B ComplexSynonyms: adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate], Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavineCarbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigational[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.
Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 InducersSynonyms: 5-Carbamoyl-5H-dibenz(b,f)azepine, 5-carbamoyl-5H-dibenz[b,f]azepineButalbital
go.drugbank.com/drugs/DB00241ApprovedIllicitButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index.
Mixtures: Butalbital and Acetaminophen 50 mg/325 mg, Fiorinal-C 1/4Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersPyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalThis is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
Mixtures: S-pan-M Tab, Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin AlgalCategories: Vitamin B Complex, Heterocyclic Compounds, 1-RingLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide