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Follitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalThe alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … However, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but
Mixtures: Menopur 75/75 I.E. - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, MENOGON 75 IU LIYOFILIZE TOZ ICEREN AMPUL,5 ADETSynonyms: FSH-a, FSH-bFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamideOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigationalOlanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent. … [A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548]
Synonyms: 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepineInternational brands: Jolyon-MDVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigationalVenlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). … [A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: VENOXOR®75 MG, Venlafab 25 mg - TablettenSultamicillin
go.drugbank.com/drugs/DB12127ApprovedWithdrawnSultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: BACMICINE® 250 MG / 5 ML, BACTESUL 250 MG/ 5 MLBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approved[A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such … [A186286] For example, buprenorphine dissociates from opioid receptors very slowly, resulting in a long duration of action and relief from pain or withdrawal symptoms for upwards of 24-36 hours.
Mixtures: SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET, SUBOXONE 2 MG/0,5 MG DILALTI TABLET, 7 ADETCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigationalDesogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. … [F4127] In the US, desogestrel is found only in combination with [ethinyl estradiol].
Synonyms: 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-olMixtures: Liberel 0,15 mg/0,03 mg Filmtabletten, Liberel mite 0,15 mg/0,02 mg FilmtablettenClomipramine
go.drugbank.com/drugs/DB01242ApprovedInvestigationalVet approvedIn depressed individuals, clomipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanaminePaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.
Synonyms: 9-hydroxyrisperidoneCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsDexketoprofen
go.drugbank.com/drugs/DB09214ApprovedInvestigationalWithdrawnDexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America.
Mixtures: Skudexa 75 mg/25 mg Filmtabletten, SKUDEXA FILM-COATED TABLET 75 MG/25 MGCategories: Non COX-2 selective NSAIDS