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Norethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigational[A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.
Synonyms: 17-α-ethynyl-19-norandrost-4-en-17-β-ol-3-one, 17-α-ethynyl-4-estren-17-ol-3-oneInternational brands: Primolut-NAdefovir dipivoxil
go.drugbank.com/drugs/DB00718ApprovedIt is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir. … dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B.
International brands: A Di Xian, A Gan DingCategories: Heterocyclic Compounds, 2-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase InhibitorAzatadine
go.drugbank.com/drugs/DB00719ApprovedWithdrawnAntihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- r...
Synonyms: 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineMixtures: X-TRI D, XL-3 VRTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine, 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepineCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigationalNitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.
Mixtures: Nitroglycerin In 5% Dextrose Inj.-400mcg/ml, Nitroglycerin In 5% Dextrose Inj.-200mcg/mlCategories: Compounds used in a research, industrial, or household settingRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigational[Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action.
Products: ESMERON® 50 MG / 5 ML, JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADETThiabendazole
go.drugbank.com/drugs/DB00730ApprovedVet approvedWithdrawn2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.
Synonyms: 2-(thiazol-4-yl)benzimidazole, 4-(2-benzimidazolyl)thiazoleCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingBeraprost
go.drugbank.com/drugs/DB05229InvestigationalBeraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.
Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: ดอร์เนอ(R) ชนิดเม็ด 20 ไมโครกรัมRotigotine
go.drugbank.com/drugs/DB05271ApprovedInvestigationalIt is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. … Rotigotine has been authorized as a treatment for RLS since August 2008.
Synonyms: (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenolCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingHistamine
go.drugbank.com/drugs/DB05381ApprovedInvestigationalIt is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.
Synonyms: 2-(4-imidazolyl)ethylamine, 4-imidazoleethylamineMixtures: Histamine DHCl 0.10 Percent and Menthol 2 Percent