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Carbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigationalIndividuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. … Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled.
Mixtures: GUAYACOLATO DE GLICERILO - CARBOXIMETILCISTEINAProducts: SOLVELIN DE ANGELI, MUCOSIS 50 MG/ML ŞURUP, 100 MLElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalat half (50 mcg) of its regular strength. … acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Synonyms: MRNA-1273 SARS-COV-2Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneAceclofenac
go.drugbank.com/drugs/DB06736ApprovedIn 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug. … It is a more commonly prescribed drug in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: AINEDIX AC® 100 MG, ACECLOFENACO 100 MG TABLETASNitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsProducts: NITRAZEPAM AL 10, NITRAZEPAM-NEURAX 10 MGIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational[L41780] Ioversol is a highly hydrophilic agent considered to be generally safe[L41790]; however, serious adverse reactions have been reported due to the inadvertent intrathecal administration of ioversol … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Categories: Compounds used in a research, industrial, or household settingInternational brands: OPTIRAY 350Cephalexin
go.drugbank.com/drugs/DB00567ApprovedInvestigationalVet approved[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. … [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigationalin pregnancy due to a perceived lower risk of teratogenic effects. … [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and is the active metabolite of the
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsProducts: THYROZOL TABLET 10 mg, PERİZOL 10 MG FİLM KAPLI TABLET, 100 ADETTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria.
Mixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg HartkapselnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsDeferiprone
go.drugbank.com/drugs/DB08826ApprovedInvestigationalThalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: FERRIPROX 100 MG/ML SURUP, 500 ML, HİERO 500 MG FİLM KAPLI TABLET, 100 ADET