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Displaying results 491 - 500 of 10000 in total
  1. Drug

    Potassium alum

    go.drugbank.com/drugs/DB09087
    ApprovedWithdrawn

    Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O).

    Mixtures: Gingicord W Epineph and Alum Size No 1, Gingicord W Epineph and Alum Size No 3Products: Gingiyarn W Alum Pot Sulf No2 0.8mg/2.5cm, Gingiyarn W Alum Pot Sulf No3 1.35mg/2.5cm
  2. Drug

    Rocuronium

    go.drugbank.com/drugs/DB00728
    ApprovedInvestigational

    It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery … Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. It is commonly marketed under the trade names Zemuron and Esmeron.

    Products: BROMURO DE ROCURONIO 25MG/2.5ML, ZEMUROC® 10MG/ML
  3. Drug

    Choline

    go.drugbank.com/drugs/DB00122
    ApprovedInvestigationalNutraceutical

    A basic constituent of lecithin that is found in many plants and animal organs. … It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

    Mixtures: Choline and Inositol 250mg/250mg, Super Daily No 2Categories: Salicylic Acid and Derivatives
  4. Drug

    Moclobemide

    go.drugbank.com/drugs/DB01171
    ApprovedInvestigational

    Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901]. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (

    Categories: Benzamides and benzamide derivatives, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamide
  5. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Phenytoin and Prodrugs, Metabolic Side Effects of Drugs and Substances
  6. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    It is typically extracted from ilmenite, rutile and anatase.

    Mixtures: May Newyork Super Sun 10g, Sun Bum Mineral Sunscreen Roll On SPF 50Categories: Astringents and Deodorants
  7. Pathway

    Metabolism and Physiological Effects of Hippuric Acid

    smpdb.ca/view/SMP0123209
    Metabolic

    It can reduce blood clotting and, in the kidney, inhibit organic acid secretion. It is associated with phenylketonuria, propionic acidemia, and tyrosinemia I (genetic metabolic disorders). … After ingestion and absorption in the gut, benzoic acid is transported into the hepatic liver cell from blood where it undergoes two metabolic reactions.

    Drugs: ATP · Benzoic acid · Pyrophosphoric acid
  8. Pathway

    Metabolism and Physiological Effects of Phenyl glucuronide

    smpdb.ca/view/SMP0123227
    Metabolic

    Phenyl glucuronide is a phenolic compound that is formed through gut microbial metabolism from dietary tyrosine and a glucuronidation reaction in liver hepatic cells.

    Drugs: Tyrosine · Phenol · Uridine-5'-Diphosphate
  9. Pathway

    Metabolism and Physiological Effects of Indoxyl glucuronide

    smpdb.ca/view/SMP0123239
    Metabolic

    Indoxyl glucuronide is an indole compound that is formed through gut microbial metabolism from dietary tryptophan and a glucuronidation reaction in liver hepatic cells.

    Drugs: Tryptophan · Indole
  10. Pathway

    Metabolism and Physiological Effects of Kynurenic Acid

    smpdb.ca/view/SMP0123300
    Metabolic

    Kynurenic acid is shown to activate aryl hydrocarbon receptors that can lead to renal impairment, and it also disrupts the electron transport chain and oxidative phosphorylation causing muscle atrophy. … After being transported into a hepatocyte from portal circulation tryptophan undergoes a reaction with the enzyme tryptophan-2,3-dioxygenase to initially form kynurenine and then with a kynurenine aminotransferase

    Drugs: Pyridoxal phosphate · Tryptophan · Kynurenine · Mesoheme