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Finerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigationalFinerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart … [A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449]
Products: KERENDIA FILM-COATED TABLET 10MG, KERENDIA FILM-COATED TABLET 20MGMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnMianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Products: MIANSERIN 10MG HOLSTEN, MIANSERIN-REMEDICA 10mg Film-Coated TabletsEszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalEszopiclone was initially approved by the FDA in 2004.[L6769]
International brands: Wen FeiProducts: LUNAX 1MG, LUNIVIA 1MG FILMTABLETTENAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigational[A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335] … It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine.
Products: AZACITIDINA EG, Vidaza powder for suspension for injection 100mg/vialPentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, with nitric acid (HNO2). The reacting solution is chilled to precipitate the PETN. … Interestingly, this drug was studied for potential benefits in chronic ischemic heart failure patients.
Categories: Vasodilators Used in Cardiac DiseasesSynonyms: TENCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigational[A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. … Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other
Products: CELECOXIB EG, CELEBREX 100MGPentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalThe drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.
Products: Nipent Pws 10mg/vialCalcium magnesium potassium carbonate chloride hydroxide
go.drugbank.com/drugs/DB14497InvestigationalSynonyms: Alka4-complexGliSODin
go.drugbank.com/drugs/DB17013InvestigationalNutraceuticalSynonyms: Gliadin-superoxide dismutase complexOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. … Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE).
Products: XOLAIR SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/1.0ML, Xolair 150mg/ml Solution for Injection in Pre-filled Syringe