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Mivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnMivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscul...
Categories: Heterocyclic Compounds, 2-RingProducts: MİVACRON 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, MIVACRON INJECTION 10 mg/5 mlPrednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approved[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Mixtures: OTIMISIN DAMLA, 10 MLSynonyms: delta(1)-Hydrocortisone, delta(1)-DehydrocortisolAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnIt was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Synonyms: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole, 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazoleCategories: Heterocyclic Compounds, 2-RingMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … [A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepineCategories: Adrenergic alpha-2 Receptor AntagonistsAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalIt is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. … [L43397] Alemtuzumab was approved by the FDA in 2001.[L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL).
Synonyms: Campath-1H, Campath 1-HProducts: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), MABCAMPATH ® 30 MG/MLBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate.
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLCategories: Heterocyclic Compounds, 1-RingDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances and other systemic adverse effects. … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: DUOSOPT FREE 20 MG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 60 ADET, Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, LösungCategories: Heterocyclic Compounds, 1-RingDiflunisal
go.drugbank.com/drugs/DB00861ApprovedThough its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway.
Categories: Non COX-2 selective NSAIDSSynonyms: 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid, 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acidDimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigationalIt is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide
Synonyms: (E)-But-2-enedioic acid dimethyl ester, 1,2-bis(methoxycarbonyl)-trans-ethyleneProducts: TECFIDERA 120 MG, YARDIX® 120 MGAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalmcg/mL in vitro. … Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0
Products: AMPHOLIP ®50 MG/10 ML, ABELCET 100 MG/20 ML IV INF. ICIN. SUS. ICEREN FLAKON, 1 ADET