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Displaying results 5001 - 5010 of 6949 in total
  1. Drug

    Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)

    go.drugbank.com/drugs/DB15863
    Experimental

    As of June, 2020, safety and Immunogenicity trials are currently underway for this vaccine (NCT04470609 & NCT04412538). … This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West China Second University Hospital, and Yunan Center for Disease Control and Prevention.

  2. Drug

    Hexamethonium

    go.drugbank.com/drugs/DB08960
    Experimental

    It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely

  3. Drug

    Smilagenin

    go.drugbank.com/drugs/DB05450
    Investigational

    P58 therefore provides a totally novel mode of action with potential importance for diseases associated with ageing of the brain. … P58 is one of a family of phytochemicals isolated from traditional treatments for the elderly that have previously been shown to offer significant benefit in the treatment of senile dementia.

  4. Drug

    Clevudine

    go.drugbank.com/drugs/DB06683
    Investigational

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  5. Drug

    Xylazine

    go.drugbank.com/drugs/DB11477
    InvestigationalVet approved

    [A32545] Xylazine is not approved for human use and requires a veterinary licence for its purchase and use. … [A9095,L42675,A251420] It acts as an agonist at α2 adrenoceptors; however, its affinity is lower than the one reported for other α2 adrenergic receptor agonists such as [detomidine] and [medetomidine].

    Categories: Adrenergic alpha-2 Receptor Agonists
  6. Drug

    YKP-1358

    go.drugbank.com/drugs/DB06109
    Experimental

    In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.

    Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor Antagonists
  7. Drug

    Vatiquinone

    go.drugbank.com/drugs/DB11917
    Investigational

    Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.

  8. Drug

    Rheinanthrone

    go.drugbank.com/drugs/DB13175
    Experimental

    Rheinanthrone is the active metabolite of senna glycoside [DB11365] known for its laxative effect [A19235]. It is commonly produced by plants of the Rheum species [L772].

  9. Drug

    Ecraprost

    go.drugbank.com/drugs/DB16148
    Investigational

    Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease).

  10. Drug

    Opiranserin

    go.drugbank.com/drugs/DB16271
    Investigational

    Opiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).

    Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists