Search
Creatinine Clearance 5-15 mL/min
go.drugbank.com/conditions/DBCOND0133572Drugs: Amino acidsSynonyms: Creatinine Clearance 5-15 mL/minDeoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Synonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acidMixtures: Debiline H, Duchol EctBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalBenralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®, Fasenra 30 mg solution for injection in pre-filled syringeIntracellular exo-alpha-(1->5)-L-arabinofuranosidase
go.drugbank.com/bio_entities/BE0001766TargetGeobacillus stearothermophilusCatalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans).
Polypeptides: Intracellular exo-alpha-(1->5)-L-arabinofuranosidaseSynonyms: Intracellular arabinan exo-alpha-(1->5)-L-arabinosidaseInterferon beta-1b
go.drugbank.com/drugs/DB00068ApprovedInvestigationalHuman interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: Interferon beta-1b, Interferon-beta-1bDoravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigational[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.
Categories: Heterocyclic Compounds, 1-Ring, Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase InhibitorProducts: PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET5-oxoprolinase
go.drugbank.com/bio_entities/BE0002268TargetEnzymeHumansCatalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate
Polypeptides: 5-oxoprolinaseSynonyms: 5-OPase, 5-oxo-L-prolinaseCadherin-5
go.drugbank.com/bio_entities/BE0003403TargetHumansCadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (Pu...
Polypeptides: Cadherin-5Nepidermin
go.drugbank.com/drugs/DB14145InvestigationalSynonyms: H-EGFInternational brands: Regen-D, Kang He SuFrizzled-5
go.drugbank.com/bio_entities/BE0014104TargetHumansReceptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By sim...
Polypeptides: Frizzled-5Synonyms: Fz-5