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Displaying results 5031 - 5040 of 10000 in total
  1. Drug

    Tropatepine

    go.drugbank.com/drugs/DB13252
    Experimental

    Tropatepine has been used in France for its antiparkinsons activities [A175024].

  2. Drug

    AZD-8330

    go.drugbank.com/drugs/DB06061
    Investigational

    AZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.

  3. Drug

    Melarsomine

    go.drugbank.com/drugs/DB11528
    ExperimentalVet approved

    It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection. … Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide.

  4. Drug

    Corticorelin

    go.drugbank.com/drugs/DB05394
    Investigational

    Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … It is a type of neurohormone, also called hCRF.

    Categories: Tests for Pituitary Function
  5. Drug

    ISF402

    go.drugbank.com/drugs/DB06315
    Experimental

    ISF402 is an investigational peptide tetramer which helps dispersal of insulin via zinc chelation, therefore allowing insulin hexamers to break free.

  6. Drug

    Malacidin B

    go.drugbank.com/drugs/DB14052
    Experimental

    Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312].

  7. Drug

    Malacidin A

    go.drugbank.com/drugs/DB14051
    Experimental

    Malacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears to act via its own distinct mechanism.

    Synonyms: Malacidin A
  8. Drug

    ATX-201

    go.drugbank.com/drugs/DB05765
    Investigational

    ATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic keratosis. … The company announced the decision to discontinue its ATX-201 clinical program for actinic keratosis.

  9. Drug

    D-Leucine

    go.drugbank.com/drugs/DB01746
    Experimental

    An essential branched-chain amino acid important for hemoglobin formation. [PubChem]

  10. Drug

    Famzeretcel

    go.drugbank.com/drugs/DB17906
    Investigational

    jCell is an human retinal progenitor cell therapy for retinitis pigmentosa.