Search

Displaying results 5061 - 5070 of 10000 in total
  1. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

    Mixtures: VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADET, VERACOMB MR 180/2 MG KAPSÜL, 28 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin System
  2. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC, VH (MUS MUSCULUS IGHV3-8*02 -(IGHD)-HOMO SAPIEN
  3. Drug

    Ceftobiprole medocaril

    go.drugbank.com/drugs/DB14733
    Approved

    Ceftobiprole medocaril is a prodrug of [ceftobiprole], a fifth-generation semisynthetic cephalosporin antibacterial. … Union primarily due to data quality issues in pivotal clinical studies.

    Categories: Heterocyclic Compounds, 2-RingProducts: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, ZEVTERA® POLVO LIOFILIZADO
  4. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: Clinimix 5 % G-E - Infusionsbeutel, SOLUCION DP PISA 2.5%(MODIFICADA EN MAGNESIO Y LACTATO)Products: Slow-mag, Slow-mag-tab
  5. Drug

    AB-22

    go.drugbank.com/drugs/DB18296
    Experimental

    Synonyms: Hydrazinecarboxamide, n-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1h-pyrazolo(3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)-, N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1h-pyrazolo(3,4-b)pyridin-6-yl)hydrazinecarboxamide
  6. Drug

    Sodium oxybate

    go.drugbank.com/drugs/DB09072
    ApprovedInvestigational

    [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA. … [A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and abuse.

    Products: Natriumoxybat Kalceks 500 mg/ml Lösung zum Einnehmen, Natriumoxybat neuraxpharm 500 mg/ml Lösung zum Einnehmen
  7. Drug

    Iocetamic acid

    go.drugbank.com/drugs/DB09403
    Approved

    Iocetamic acid is a diagnostic aid (radiopaque medium)

    Categories: X-Ray Contrast Media, Iodinated, Watersoluble, Hepatotropic X-Ray Contrast MediaProducts: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)
  8. Drug

    Gadobenic acid

    go.drugbank.com/drugs/DB00743
    ApprovedInvestigational

    Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.

    Mixtures: MULTIHANCE INJECTION 10 ML, MULTIHANCE INJECTION 10 MLCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Terconazole

    go.drugbank.com/drugs/DB00251
    Approved

    Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a _triazole ketal derivative_. … [A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole.

    Mixtures: TEREX-3, Terazol 3 Dual PakCategories: Heterocyclic Compounds, 1-Ring
  10. Target

    5'-AMP-activated protein kinase subunit beta-1

    go.drugbank.com/bio_entities/BE0000254
    TargetHumans

    Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-pro...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1Synonyms: AMPK subunit beta-1