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AB-22
go.drugbank.com/drugs/DB18296ExperimentalSynonyms: Hydrazinecarboxamide, n-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1h-pyrazolo(3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)-, N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1h-pyrazolo(3,4-b)pyridin-6-yl)hydrazinecarboxamidePost-essential Thrombocythemia Myelofibrosis (Post-ET MF)
go.drugbank.com/conditions/DBCOND0069581Drugs: RuxolitinibSynonyms: Post ET MF, Post-ET MFSodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnGold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. … Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects.
Products: MYOCRISIN INJECTION 20 MG (4% W/V), MIOCRIN 50 MGSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. … [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243]
Mixtures: SPIRO D TABLINEN 100MG, Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2%Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalThe first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells. … Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake
Categories: Human Immunodeficiency Virus 1 Fusion Inhibitor, Cytochrome P-450 SubstratesProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MIInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigationalInsulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … [A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Levemir FlexPen 100U/ML Solution for injection in a prefilled pen, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled PenGaucher Disease, Type 1
go.drugbank.com/conditions/DBCOND0035324Synonyms: Gaucher Disease, Type 1, Type 1 Gaucher DiseaseType 1 Diabetes Mellitus
go.drugbank.com/conditions/DBCOND0029465Drugs: Donislecel · Insulin degludec · Insulin detemir · Insulin glargine · Insulin glulisine · Insulin human +3 moreSynonyms: Diabete Type 1, Type 1 DiabetesAlpha-1 Anti-trypsin Deficiency
go.drugbank.com/conditions/DBCOND0066043Synonyms: Alpha-1 AT Deficiency, Alpha-1-antitrypsin-deficiencyChronic Hepatitis C Genotype 1
go.drugbank.com/conditions/DBCOND0053690Synonyms: Genotype 1, Chronic Hepatitis C Genotype 1