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Displaying results 501 - 510 of 10000 in total
  1. Drug

    Attapulgite

    go.drugbank.com/drugs/DB01574
    ApprovedVet approvedWithdrawn

    Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications.

    Mixtures: Diban Cap, Diban CapCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Arginine

    go.drugbank.com/drugs/DB00125
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is physiologically active in the L-form.

    Synonyms: (S)-2-amino-5-guanidinopentanoic acid, (S)-2-Amino-5-guanidinovaleric acidInternational brands: R-Gene 10
  3. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    [label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors. … [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in 1956.

    Synonyms: Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine, N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Asparaginase Escherichia coli

    go.drugbank.com/drugs/DB00023
    ApprovedInvestigational

    Asparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].

    Synonyms: Asparaginase II, L-AsnaseProducts: KIDROLASE 10000 UI, LEUNASE ENJEKTABL 10.000 IU FLAKON, 1 ADET
  5. Drug

    Idarubicin

    go.drugbank.com/drugs/DB01177
    ApprovedInvestigational

    An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

    Categories: Topoisomerase II Inhibitors, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, 4-Demethoxydaunomycin
  6. Drug

    Prazosin

    go.drugbank.com/drugs/DB00457
    ApprovedInvestigational

    Prazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. … [L5828] It belongs to the class of drugs known as alpha-1 antagonists.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline
  7. Drug

    Bemiparin

    go.drugbank.com/drugs/DB09258
    ApprovedInvestigationalWithdrawn

    Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). … Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866].

    Products: HIBOR® 3.500 UI., HIBOR® 10.000 UI
  8. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: ALPHANATE FOR INJECTION 250 iu/vial, ALPHANATE FOR INJECTION 1000 iu/vialProducts: DRIED FACTOR VIII FRACTION 500 UI + FACTOR DE VON WILLEBRAND 800 UI, FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET
  9. Drug

    (3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE

    go.drugbank.com/drugs/DB07964
    Experimental

    Synonyms: (3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE
  10. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and reduction of vasoconstrictor adrenergic signals. … [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects.

    Categories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistSynonyms: α-methyl-L-dopa, 3-Hydroxy-alpha-methyl-L-tyrosine