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Leflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Products: LEFLUNOMID 1A PHARMA 10MG, LEFLUNOMID 1A PHARMA 20MGBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Taurine
go.drugbank.com/drugs/DB01956ApprovedInvestigationalNutraceuticalTaurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured b...
Mixtures: AA-VenCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalThe relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Mixtures: Ala-hist Ac, Virtussin A/CSynonyms: L-CodeineVoretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigational[L1094] An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. … [A31477] An advantage of this adeno-associated virus is the high predictability, unlike retrovirus, as they associate with a specific region of the human cellular genome localized in the chromosome 19.
Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalProducing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. … The potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation.
Products: RIBAVIRINA ROCHE CAPSULAS 200 MG, COPEGUS ROCHE 400 MG FILM KAPLI TABLET, 14 ADETDinutuximab
go.drugbank.com/drugs/DB09077ApprovedInvestigationalDespite a high clinical response seen after first-line treatment, the complete eradication of neuroblastoma is rarely achieved and the majority of patients with advanced disease suffer a relapse. … neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
Dimethicone 410
go.drugbank.com/drugs/DB14005ApprovedDimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products.[A32462] It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit. … [L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%.
Quinidine
go.drugbank.com/drugs/DB00908ApprovedThis alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species.
Categories: Antiarrhythmics, Class Ia, P-glycoprotein substrates with a Narrow Therapeutic IndexCariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigational[A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT<sub>1A</sub> receptors and as an antagonist at serotonin 5-HT<sub>2A</sub> receptors. … Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary.