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Polymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B was discovered in the 1940s[A176429]. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes[A176426].
Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticProducts: POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 10 FLAKON, POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 1 FLAKONTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigational[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943] … Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
International brands: Testaqua IMProducts: Androgel 25 mg transdermales Gel im Beutel, Androgel 50 mg transdermales Gel im BeutelAnidulafungin
go.drugbank.com/drugs/DB00362ApprovedAnidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. … There is preliminary evidence that it has a similar safety profile to caspofungin.
Products: ERAXIS 100 MG INF. COZ. ICIN TOZ ICEREN FLAKON, 1 ADET VE COZUCU, FİGOLYZ 100 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADETIotrolan
go.drugbank.com/drugs/DB09487ApprovedWithdrawnNonionic, isotonic contrast medium designed for intrathecal use.
Categories: Compounds used in a research, industrial, or household settingProducts: Osmovist 240 - Liq Int 513mg/ml, Osmovist 300 - Liq Int 641mg/mlFosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. … Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant.
Products: Emend IV, EMEND IVCefamandole nafate
go.drugbank.com/drugs/DB14725ApprovedWithdrawnProducts: Mandol Inj 2gm/amp, Mandol Inj 1gm/ampTubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216028] It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular blockade during surgeries, particularly those involving the abdomen. … [A216048] Safer and more pharmacokinetically favorable non-depolarizing neuromuscular blockers, such as [rocuronium], have largely replaced the use of tubocurarine in the clinical setting.[A216048]
Products: Tubocurarine Chloride Inj 3mg/ml, Tubocurarine Chloride Inj 3mg/ml USPEnflurane
go.drugbank.com/drugs/DB00228ApprovedVet approvedWithdrawnIn addition, it is known to cause increased cardio depressant effects when compared to other inhaled anesthetics.[A202022] … Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.
Products: Ethrane Liq Inh, Ethrane Liquid InhTopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: Topoisomerase I InhibitorsProducts: TOPOXIN 4 MG IV INF.ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, HYCAMTIN IV LİYOFİLİZE TOZ İÇEREN ENJEKTABL FLAKON, 1 ADETKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Products: Toradol Im, Toronova II SUIK