Cefamandole nafate

DB14725ApprovedWithdrawnSmall molecule

Cefamandole nafate is a second generation cephalosporin indicated in the prevention of infections during surgery. An antibiotic used to prevent infections in surgery.

Chemical structure of Cefamandole nafate
Mechanism
Curator reviewed
Formula / weight
C19H18N6O6S2 · 490.51 g/mol (avg)
First approval
Canada, 1978
Also known as
O-formylcefamandole

Resolves to

Compound
UNII3L768V9MWVCAS57268-80-1ChEMBLCHEMBL1201218ChEBI53654
Clinical / RWD
RxNorm20473
Structure
InChIKeyRRJHESVQVSRQEX-SUYBPPKGSA-NSMILES[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)[C@H](OC=O)C1=CC=CC=C1)C(O)=O

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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125Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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4Marketed productsAcross 2 countries and 2 labellers
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4+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Cefamandole nafate, and which companies have late-stage candidates in those indications?

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