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Displaying results 501 - 510 of 9613 in total
  1. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    It is indicated for the treatment of various inflammatory disorders such as adult or pediatric Chron's disease, adult or pediatric ulcerative colitis, rheumatoid arthritis in combination with methotrexate … Infliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection.

    Products: INFLECTRA 100MG PLV F E KO, REMICADE 100MG PUL HER INF
  2. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position. … [L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone.

    Products: Andriol Testocaps Capsules 40mg, PMS-testosterone
  3. Drug

    Trihexyphenidyl

    go.drugbank.com/drugs/DB00376
    ApprovedInvestigational

    [L31843] It has largely been replaced by drugs such as [levodopa].[L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768] … [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.

    International brands: Ea TenProducts: PMS-trihexyphenidyl, PMS Trihexyphenidyl
  4. Target

    Endothelial PAS domain-containing protein 1

    go.drugbank.com/bio_entities/BE0009679
    TargetHumans

    Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). ...

    Polypeptides: Endothelial PAS domain-containing protein 1Synonyms: Member of PAS protein 2, PAS domain-containing protein 2
  5. Drug

    Somapacitan

    go.drugbank.com/drugs/DB15093
    ApprovedInvestigational

    [A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666] … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.

    Products: SOGROYA® 10MG/1.5ML, SOGROYA® 5MG/1.5ML
  6. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

    Products: FULTRANT ® 250MG/ 5ML SOLUCIÓN PARA INYECCIÓN EN JERINGA PRELLENADA, FASLODEX SOLUTION FOR INJECTION 250MG/5 ML
  7. Drug

    Zinc citrate

    go.drugbank.com/drugs/DB11154
    ApprovedInvestigational

    It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.

    Mixtures: Collag-EN, EC + ComplexProducts: Zinc Tab 15mg, Zinc Citrate Tab 15mg
  8. Drug

    Posaconazole

    go.drugbank.com/drugs/DB01263
    ApprovedInvestigationalVet approved

    Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.

    Products: Posaconazol Sandoz 40mg/ml - Suspension zum Einnehmen, NOXAFIL TABLET 100MG
  9. Drug

    Cilazapril

    go.drugbank.com/drugs/DB01340
    ApprovedInvestigational

    It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States. … It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.

    Products: Inhibace Tab 1mg, PMS-cilazapril
  10. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    It was initially approved by the FDA in 1991 [A174175]. … It is structurally related to erythromycin [A174169].

    Products: Azyter 15mg/g Eye Drops, Zithromax - Pws Orl 100mg/5ml