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Linagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated b...
Mixtures: TRAYENTA DUO, TRAJENTA DUOCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesAcetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigational[L5783] Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines … [L5786,L5789,L4396] On September 22, 2025, the US FDA initiated a labeling change for acetaminophen products suggesting that the use of acetaminophen by pregnant women may be associated with an increased
Synonyms: p-acetamidophenol, p-acetaminophenolInternational brands: Oraphen-PDAmylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnDespite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, ...
Products: Dentition Sirop DeMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: MIZOLEN 10 MG TABLETAS DE LIBERACION PROLONGADAPizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Products: Sandomigran DSLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalan important role in tumor cell growth and survival. … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: VITRAKVI®CÁPSULAS DE 100MGBiropepimut-S
go.drugbank.com/drugs/DB14816InvestigationalBiropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity).
Synonyms: LYS-VAL-ALA-GLU-LEU-VAL-HIS-PHE-LEU-ARG-VAL-LYS-ARG-PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL-ARG-VAL-LYS-ARG-VAL-ILE-PHE-SER-LYS-ALA-SER-SER-SER-LEU-GLN-LEU-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARGVemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigationalVemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxiko...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MGSecukinumab
go.drugbank.com/drugs/DB09029ApprovedInvestigationalSecukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions ...
Products: COSENTYX POWDER FOR SOLUTION FOR INJECTION 150MG/VIALDimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigational[L32995] Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery.
Products: VOTMINE INJECTION 10ML VIAL (50MG/ML), VOTMINE INJECTION 10 ML VIAL (50MG/ML)