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Displaying results 5091 - 5100 of 5922 in total
  1. Drug

    Sphingosine

    go.drugbank.com/drugs/DB03203
    Investigational

    An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)

    Categories: P-glycoprotein substrates
  2. Drug

    Cephalothin Group

    go.drugbank.com/drugs/DB03450
    Experimental

    This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine carboxypeptidase.

  3. Drug

    Equilenin

    go.drugbank.com/drugs/DB03515
    Experimental

    Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine of pregnant mares.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Ribostamycin

    go.drugbank.com/drugs/DB03615
    ApprovedWithdrawn

    Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosidificus listed as one of the World Health Organization's critically important antimicrobials.

  5. Drug

    alpha-D-quinovopyranose

    go.drugbank.com/drugs/DB03773
    Experimental

    The pyranose form of D-quinovose with an α-configuration at the anomeric position .

    Synonyms: D-Chinovose, D-Epifucose
  6. Drug

    Plicamycin

    go.drugbank.com/drugs/DB06810
    ApprovedWithdrawn

    Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued pl...

  7. Drug

    Brefeldin A

    go.drugbank.com/drugs/DB07348
    Experimental

    A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  8. Drug

    (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE

    go.drugbank.com/drugs/DB07621
    Experimental

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  9. Drug

    Formestane

    go.drugbank.com/drugs/DB08905
    ApprovedWithdrawn

    Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or pro...

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  10. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant

    Synonyms: D-Limonen, D-limonene