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Granisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAfimoxifene
go.drugbank.com/drugs/DB04468InvestigationalIt is being developed by Ascent Therapeutics.
Metiamide
go.drugbank.com/drugs/DB08805ExperimentalIt was an intermediate product on the path to developing cimetidine.
Brofaromine
go.drugbank.com/drugs/DB13876ExperimentalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome2,5-Dimethoxy-4-ethylthioamphetamine
go.drugbank.com/drugs/DB13940Experimental2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCry5B
go.drugbank.com/drugs/DB17783ExperimentalCry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_.
AZD-8186
go.drugbank.com/drugs/DB15029Investigationalinvestigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by
2X-121
go.drugbank.com/drugs/DB16063Investigational2X-121 is under investigation in clinical trial NCT03562832 (Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the
SR 140333
go.drugbank.com/drugs/DB05790ExperimentalSR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Licofelone
go.drugbank.com/drugs/DB04725ExperimentalDeveloped by the German pharmaceutical company, Merckle GmbH, together with EuroAlliance partners Alfa Wassermann and Lacer, licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this … Although phase III trials have been successfully completed in OA patients no dates for regulatory submission have yet been given.