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Displaying results 5121 - 5130 of 10000 in total
  1. Drug

    Stavudine

    go.drugbank.com/drugs/DB00649
    ApprovedInvestigational

    A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

    Synonyms: 2',3'-Didehydro-3'-deoxythimidine, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymineInternational brands: Ai Fu Ding
  2. Drug

    Ponatinib

    go.drugbank.com/drugs/DB08901
    ApprovedInvestigational

    Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS, ICLUSIG TABLET 45 MG
  3. Drug

    Ritodrine

    go.drugbank.com/drugs/DB00867
    ApprovedWithdrawn

    Adrenergic beta-agonist used to control premature labor.

    Categories: Adrenergic beta-2 Receptor AgonistsSynonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol
  4. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].

    Mixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, SAEROGENTA-A CREAMCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  5. Drug

    Alogliptin

    go.drugbank.com/drugs/DB06203
    ApprovedInvestigational

    Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.

    Mixtures: INCRESINA P, OSENI 25 MG/15 MG TABLETSCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  6. Drug

    Methenamine

    go.drugbank.com/drugs/DB06799
    ApprovedInvestigationalVet approved

    Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).

    Mixtures: UR N-C Urinary Antiseptic, PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GRProducts: NETURONE GRANUL LIBA, 70 G, NETURONE GRANUL LIBA, 105 G
  7. Indication

    Stage IV Non-small Cell Lung Cancer (NSCLC)

    go.drugbank.com/conditions/DBCOND0122752
    Drugs: Gemcitabine
    Synonyms: Stage 4 NSCLC, Stage 4 Non-small cell lung cancer
  8. Drug

    Pinaverium

    go.drugbank.com/drugs/DB09090
    ApprovedInvestigational

    Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. … Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries including Canada.

    Mixtures: BROMUX D® 100/300 MG CÁPSULA., DUOTRYNE®Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  9. Drug

    Entacapone

    go.drugbank.com/drugs/DB00494
    ApprovedInvestigational

    Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. … of levodopa and a decarboxylase inhibitor.

    Mixtures: LEVO/CA/EN 100/25/200 STD, LEVO/CA/EN 150/37.5/200STDCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  10. Drug

    Chondroitin sulfate

    go.drugbank.com/drugs/DB09301
    ApprovedInvestigationalNutraceutical

    Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific … [A7906] The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment.

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: HIRUDOID FORT %0,445 JEL, 40 G, HIRUDOID FORT %0,445 KREM, 40 G