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Displaying results 511 - 520 of 6183 in total
  1. Drug

    ALLO-715

    go.drugbank.com/drugs/DB18640
    Investigational

    ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).

    Synonyms: Allogenic Chimeric Antigen Receptor T Cells Targeting B Cell Maturation Antigen (BCMA)
  2. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    (TCR) specific for the human MAGE-A4. … [L51114, L51119] Afamitresgene autoleucel is first prepared from the patient’s peripheral blood mononuclear cells (PBMCs), which are enriched for T cells and are then transduced with a replication-incompetent

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  3. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    [L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.

    Products: 400 mg Powder for injection / infusion, Convulex 50 mg/ml - Sirup für Kinder
  4. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    Bacitracin is a combination of at least 9 bacitracins. 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named M...

    Mixtures: Polysporin for StitchesCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use
  5. Drug

    Cyclosporine

    go.drugbank.com/drugs/DB00091
    ApprovedInvestigationalVet approved

    Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. … [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]

    Products: ATOPICA 25MG SOFT CAPSULES FOR DOG, ATOPICA 50MG SOFT CAPSULES FOR DOG
  6. Drug

    Tolevamer

    go.drugbank.com/drugs/DB01344
    Approved

    Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical ...

    Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: <p>KALQUEST&reg; Powder for Oral Suspension 5g/sachet</p>, PMS-SODIUM POLYSTYRENE SULFONATE POWDER FOR SUSPENSION 94.3 mg/g
  7. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients … [L7958] Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure.

    Categories: Antihypertensive Agents Indicated for HypertensionProducts: FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 50 MG/5 ML, FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 20 MG/2 ML
  8. Drug

    Mitoxantrone

    go.drugbank.com/drugs/DB01204
    ApprovedInvestigational

    An anthracenedione-derived antineoplastic agent.

    Products: MITOXANTRONE BAXTER SOLUTION FOR INJECTION 20MG/10ML (2MG/ML)
  9. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often com...

    Mixtures: Soleil Suisse Cellular Self Tan for The Face SPF 15, Soleil Suisse Cellular Self Tan for The Body SPF 15Categories: Protectives Against UV-Radiation for Topical Use
  10. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    It was developed by Genentech as a drug for the treatment of cancers … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer