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Hydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing … Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution.
Mixtures: Defense AG Disinfectant, Defense AG DisinfectantCategories: Compounds used in a research, industrial, or household settingVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigationalVoriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsProducts: VORICONAZOL AL 50MG, VORICONAZOL AL 200 MGTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Envarsus Pa, PROGRAF 5 MG/ML KONSANTRE IV INFUZYON ICIN SOLUSYON ICEREN AMPUL, 10 ADETLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalLevothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. … [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein inducersProducts: L THYROXIN AL 50UG TABL, L THYROXIN AL 100UG TABLAlbumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalThis is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. … Each domain comprises two separate sub-domains (A and B) [A40060].
Products: BUMINATE ALBUMINA AL 20 %, ALBUMINA HUMANA NORMAL AL 20%Ticagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigational[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug. … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. Ticagrelor was granted EMA approval on 3 December 2010.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Ag-ticagrelorLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedIt is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3. … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.
Mixtures: DIANEAL PD-2 CON DEXTROSA AL 1.5%., DIANEAL PD-2 CON DEXTROSA AL 1.5%.Dasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigationalDasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias. … [A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalSerplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsDocusate
go.drugbank.com/drugs/DB11089ApprovedRecently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912]. … Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative.
Products: Lax-A Soft, Ag-docusate Sodium