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Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [A199002] Daratumumab was granted FDA approval on 16 November 2015.
Products: DARZALEX 100 MG/5 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, DARZALEX 400 MG/20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTREClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawntreatments such as [rifampicin] and [isoniazid]. … It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin and bodily fluids.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: CLOFZIMIN® 100 MG, Fazim 50 mg CapsuleTucatinib
go.drugbank.com/drugs/DB11652ApprovedInvestigationalIt was developed by Seattle Genetics and approved by the FDA on April 17, 2020.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: TUKYSA 150 mg film-coated tablets, TUKYSA (TUCATINIB) FILM-COATED TABLETS 150 mgTerbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088] … Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s and early 1970s.
Mixtures: BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 ML, BRELAX 1,5 MG+66,5 MG/5 ML ŞURUP, 100 MLProducts: BRICANYL 2.5 MG TABLET, 50 TABLET, XORLAC ŞURUP, 100 CCIsatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigationalFollowing three consecutive years on the yearly "Antibodies to watch" list published in "mAb", a peer-reviewed scientific journal dedicated to antibody research,[A38676,A191826,A191829] isatuximab was
Products: SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SARCLİSA 500 MG/25 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIt is currently used as an immunosuppressant to prevent rejection of organ transplants. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 40-O-(2-hydroxyethyl)-rapamycinAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure [A175321].
Synonyms: Amlodipine free base, (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylateInternational brands: Amlodipin-Mepha 5/10, Amlodipine 5Urea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalRadiolabelled urea is available in two forms as 13C and 14C. … It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as Pranactin-Citric) for the detection of Helicobacter pylori infections.
Products: Diabact UBT 50 mg Tabletten, Tablet 100 mgRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalRiluzole is marketed as Rilutek by Sanofi. … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML, RILUTEK 50 MGCiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnIt has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Synonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholineProducts: Citicor 1000 mg/4 mL IM/IV Enjeksiyonluk Çözelti (5 adet), RONOCİT 1000 MG/4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET