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Displaying results 5191 - 5200 of 10000 in total
  1. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    It works by inhibiting DNA topoisomerases, type I.

    Synonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinCategories: Topoisomerase I Inhibitors, MATE 1 Substrates with a Narrow Therapeutic Index
  2. Drug

    Adrafinil

    go.drugbank.com/drugs/DB08925
    ApprovedWithdrawn

    Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. … Adrafinil is metabolized to [modafinil].

  3. Drug

    Amelubant

    go.drugbank.com/drugs/DB06248
    Investigational

    Synonyms: Carbamic acid, N-[[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]phenyl]iminomethyl]-, ethyl ester
  4. Drug

    Pleconaril

    go.drugbank.com/drugs/DB05105
    Investigational

    Pleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Cyclopenthiazide

    go.drugbank.com/drugs/DB13532
    Approved

    It is a positive allosteric modulator at AMPA-A receptors [T28]. … Cyclopenthiazide is a thiazide diuretic with antihypertensive properties.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Beta-(1,3)-D glucan

    go.drugbank.com/drugs/DB16468
    Investigational

    Synonyms: Tak-N, TAK (polysaccharide)
  7. Drug

    IRX-5183

    go.drugbank.com/drugs/DB05653
    Investigational

  8. Drug

    Ditazole

    go.drugbank.com/drugs/DB08994
    ApprovedWithdrawn

    Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas. … Ditazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanol
  9. Drug

    Berberine

    go.drugbank.com/drugs/DB04115
    ApprovedInvestigationalWithdrawn

    An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. … It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.

    Categories: MATE 1 Substrates, P-glycoprotein substrates
  10. Drug

    BI 2536

    go.drugbank.com/drugs/DB16107
    Investigational

    BI 2536 is under investigation in clinical trial NCT00376623 (Efficacy and Safety of BI 2536 in Advanced or Metastatic Non Small Cell Lung Cancer).

    Categories: Heterocyclic Compounds, 2-Ring