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OBE101
go.drugbank.com/drugs/DB05080ExperimentalObecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment of obese individuals and for other weight management indications. … OBE101 is a new weight loss drug developed by Obecure Ltd. It is a new formulation that is based on the vertigo medication, Betahistine.
Butobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Categories: Hypnotics and SedativesOtilonium
go.drugbank.com/drugs/DB13500InvestigationalMixtures: SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 90 ADET, BROMURO DE OTILONIO + SIMETICONA 40MG + 200MGCategories: Alimentary Tract and Metabolism, Calcium-Regulating Hormones and AgentsDepulfavirine
go.drugbank.com/drugs/DB18890InvestigationalDepulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).
Huperzine A
go.drugbank.com/drugs/DB04864ApprovedInvestigationalWithdrawnThe botanical has been used in China for centuries for the treatment of swelling, fever and blood disorders. Recently in clinical trials in China, it has demonstrated neuroprotective effects. … It is currently being investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer’s disease.
Deramciclane
go.drugbank.com/drugs/DB06512InvestigationalDeramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target. … It antagonizes 5-HT2A receptors, agonizes 5-HT2C receptors, and functions as a GABA reuptake inhibitor.
Micronomicin
go.drugbank.com/drugs/DB13274ApprovedMicronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Mepenzolate
go.drugbank.com/drugs/DB04843ApprovedWithdrawnIt decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion.
Categories: Alimentary Tract and MetabolismArbaclofen Placarbil
go.drugbank.com/drugs/DB08892InvestigationalIt was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties. … by XenoPort in 2011 for the treatment of GERD.