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Displaying results 5191 - 5200 of 8010 in total
  1. Drug

    Troxacitabine

    go.drugbank.com/drugs/DB04961
    Investigational

    There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.

  2. Drug

    Etidocaine

    go.drugbank.com/drugs/DB08987
    Approved

    Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

  3. Drug

    AVI-5126

    go.drugbank.com/drugs/DB05726
    Investigational

    AVI-526 is an improved formulation of [AVI-4557], developed for use on Vein Grafts before use in Heart by-Pass Graft Surgery. … AVI-526 works by silencing a gene known as c-myc, a key regulatory gene involved in cardiovascular restenosis.

  4. Drug

    LLL-3348

    go.drugbank.com/drugs/DB05771
    Experimental

    The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable plaque type psoriasis.

  5. Target

    Cytochrome P450 2C8

    go.drugbank.com/bio_entities/BE0002887
    TargetEnzymeHumans

    It is the principal enzyme responsible for the metabolism of the anti-cancer drug paclitaxel (taxol) (PubMed:26427316) … Metabolizes all trans-retinoic acid toward its 4-hydroxylated form (PubMed:11093772).

    Synonyms: Cytochrome P450 form 1
  6. Drug

    Dirlotapide

    go.drugbank.com/drugs/DB11399
    InvestigationalVet approved

    It is marketed by Pfizer and Zoetis under the brand name, _Slentrol_, and is not intended for human use.

  7. Drug

    Thiostrepton

    go.drugbank.com/drugs/DB11467
    InvestigationalVet approved

    Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii.

  8. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

  9. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]

  10. Drug

    FB-101

    go.drugbank.com/drugs/DB17956
    Investigational

    Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).[L47102]