Search
Tranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalIt possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidInternational brands: Cyclo-FRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229708] Due to a large number of patients with myeloproliferative neoplasms who have JAK2 mutations, ruxolitinib was the first ATP-competitive inhibitor of JAK1 and JAK2 ever developed. … Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: JAKAVI 5 MG (TABLETS), JAKAVI 5 MG TABLET, 56 TABLETGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [A252195] Ganirelix was first approved by the FDA on July 29, 1999.[L43070]
Products: ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ORGALUTRAN 0,25 MG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETPomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalFDA approved on February 8, 2013.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: POMALYST 2 MG, POMALEM 2 MG SERT KAPSÜL, 21 ADETMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigationalIt inhibits the actions of interleukin-23 (IL-23), a pro-inflammatory cytokine that activates pathways contributing to the development of inflammatory diseases. … Mirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis.
Categories: Interleukin-23 AntagonistProducts: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 6 ADETTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
Mixtures: VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADET, VERACOMB MR 180/2 MG KAPSÜL, 28 ADETCategories: Heterocyclic Compounds, 2-RingValerian
go.drugbank.com/drugs/DB13196ApprovedValerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance. … Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood.
Mixtures: VALERIANA E LUPPOLO DISPERT, VALERIANA E LUPPOLO DISPERTCategories: Cytochrome P-450 CYP2C19 Inducers, Cytochrome P-450 CYP3A InducersNatalizumab
go.drugbank.com/drugs/DB00108ApprovedInvestigationalNatalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. … [A261331] On August 24, 2023, the first biosimilar to natalizumab, natalizumab-sztn, was approved by the FDA.[L48041] Natalizumab was approved by the European Commission on September 22, 2023.
Synonyms: IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMER, IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMERProducts: Tysabri 150 mg SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (2 adet), TYSABRI 300 MG I.V. INFUZYON ICIN KONSANTRE COZELTI ICEREN FLAKON, 1 ADETLomefloxacin
go.drugbank.com/drugs/DB00978ApprovedLomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs).
Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesSynonyms: (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acidSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: L-Deprenalin