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Leukotriene C4
go.drugbank.com/drugs/DB08855Experimental(From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycineMetenkefalin
go.drugbank.com/drugs/DB12668Investigational[A203225] It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. … [A203210] Metenkefalin, along with [tridecactide], are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Plozalizumab
go.drugbank.com/drugs/DB12520InvestigationalThe recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis. … Preclinical studies suggest that CCR2 plays an important role in the trafficking of monocytes and macrophages to sites of inflammation.
GX-19 Vaccine
go.drugbank.com/drugs/DB15891InvestigationalAs of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488]. … The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758].
Washed Microbiota Transplantation
go.drugbank.com/drugs/DB15745InvestigationalThe resulting suspension is shown to decrease FMT-related adverse events. … Washed microbiota preparation (WMT) involves a method wherein FMT is used, but the preparation undergoes microfiltration through an automatic purification system combined with repeated centrifugation and
Edivoxetine
go.drugbank.com/drugs/DB09184InvestigationalEdivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012. … Edivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant
Ritiometan
go.drugbank.com/drugs/DB13267ApprovedRitiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.
Alphacetylmethadol
go.drugbank.com/drugs/DB01555ExperimentalIllicitA narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome