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Arotinolol
go.drugbank.com/drugs/DB09204InvestigationalArotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy. Artinolol is being developed by Sumito...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesAranidipine
go.drugbank.com/drugs/DB09229ExperimentalAranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-n...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBenidipine
go.drugbank.com/drugs/DB09231InvestigationalBenidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and a...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsDarodipine
go.drugbank.com/drugs/DB09234ExperimentalDarodipine is a calcium channel blocker.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesImidafenacin
go.drugbank.com/drugs/DB09262InvestigationalImidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the traden...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOmbitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalOmbitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSolithromycin
go.drugbank.com/drugs/DB09308InvestigationalSolithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTegafur-uracil
go.drugbank.com/drugs/DB09327ApprovedTegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4. It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. It is approved in different...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesFluprednisolone
go.drugbank.com/drugs/DB09378ApprovedA synthetic glucocorticoid with anti-inflammatory properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMeprednisone
go.drugbank.com/drugs/DB09383ApprovedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers