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Ponatinib
go.drugbank.com/drugs/DB08901ApprovedInvestigationalPonatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS, ICLUSIG TABLET 15 MGEnzalutamide
go.drugbank.com/drugs/DB08899ApprovedInvestigational[A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was initiated in July 2007. … [L40639] It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: Enzalutamid 1A Pharma 40 mg - Filmtabletten, Enzalutamid 1A Pharma 80 mg - FilmtablettenMagnesium cation
go.drugbank.com/drugs/DB01378ApprovedInvestigationalNutraceuticalWithdrawnMagnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. … When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend
Mixtures: MAGVEL 365 MG GRANÜL İÇEREN SAŞE, 10 ADET, KALSİMAG-D3 1000 MG/300 MG/880 IU EFERVESAN GRANÜL, 30 ADETSynonyms: Magnesium, ion(Mg2+)Mangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnMangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. … Teslascan has been removed from the Drug Product List by FDA in 2003, and withdrawn from the European market in 2012.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: TESLASCAN 0,01MMOL 50 ML FLAKON, 1 ADETHexylresorcinol
go.drugbank.com/drugs/DB11254ApprovedHexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. … It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic.
Synonyms: 4-hexylresorcinol, 4-hexyl-1,3-benzenediolProducts: -s.miel Et Eucalypt., Myxcin-CChondroitin sulfate
go.drugbank.com/drugs/DB09301ApprovedInvestigationalNutraceuticalChondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific … [A32063] Chondroitin sulfate is sold as an OTC dietary supplement in North America and it is a prescription drug under the EMA in Europe.[A32066]
Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: HIRUDOID FORT %0,445 JEL, 40 G, HIRUDOID FORT %0,445 KREM, 40 GTechnetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalPertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. … This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted
Mixtures: TECHNELITE® GENERADOR DE TECNECIO TC 99M, GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQCategories: Compounds used in a research, industrial, or household settingChlorprothixene
go.drugbank.com/drugs/DB01239ApprovedInvestigationalWithdrawnChlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. … Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: Truxal 15 mg - Filmtabletten, Truxal 50 mg - Filmtabletten3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
go.drugbank.com/bio_entities/BE0000051TargetEnzymeHumansA bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis.
Polypeptides: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1Synonyms: Delta-5-3-ketosteroid isomerase, 3-beta-hydroxy-5-ene steroid dehydrogenaseEltrombopag
go.drugbank.com/drugs/DB06210ApprovedInvestigationalITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. … Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: REVOLADE ® TABLETAS 50 MG, REVOLADE® TABLETAS 25 MG