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Displaying results 5241 - 5250 of 8010 in total
  1. Drug

    CXD101

    go.drugbank.com/drugs/DB16182
    Investigational

    CXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).

  2. Drug

    Erythroxylum catuaba bark

    go.drugbank.com/drugs/DB14300
    Investigational

    "Catuaba" is a general term for a medicinal infusion created by the bark of plants belonging to the _Erythroxylum_ genus, though this name is also applied to infusions of plants belonging to other genera … [A215262] The infusion is thought to carry stimulant and aphrodisiac effects,[A215262] and catuaba made specifically with _Trichilia catigua_ has been investigated for use in depression.[A215267]

  3. Drug

    Perfluorodecalin

    go.drugbank.com/drugs/DB16292
    Investigational

    is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From

  4. Drug

    AVR118

    go.drugbank.com/drugs/DB04979
    Investigational

    of cancers); for its ability to stimulate the immune system to attack tumor cells (especially those cancer cells that have been damaged by chemotherapeutic agents) and for its ability to treat cachexia … AVR118 is being studied for the promise shown in its ability to mitigate the toxic side effects of other drugs (including those used to treat HIV infection and chemotherapeutic drugs employed in the treatment

  5. Drug

    CERE-110

    go.drugbank.com/drugs/DB05898
    Investigational

    This drug is developed by Ceregene and currently under phase I of clinical trial.

  6. Drug

    Diphenidol

    go.drugbank.com/drugs/DB01231
    ApprovedWithdrawn

    Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.

  7. Drug

    Carbomer homopolymer type C

    go.drugbank.com/drugs/DB14091
    Investigational

    Carbomer homopolymer type C is a high molecular polyanionic substance tested for antiulcerogenic activity.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Esmirtazapine

    go.drugbank.com/drugs/DB06678
    Investigational

    Merck has terminated its internal clinical development program for esmirtazapine as of March 2010. … Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause.

  9. Pathway

    mTOR Signaling pathway

    smpdb.ca/view/SMP0535455
    Signaling

    Cellular energy status is sensed by AMPK, which upon activation by a high AMP/ATP ratio phosphorylates TSC2 and the mTORC1 subunit Raptor to inhibit mTORC1, whereas high ATP from glycolysis suppresses … Amino acids signal through distinct routes: Leucine binds to CASTOR1 to dissociate it from GATOR2, blocking GATOR1 and enabling RagA/B‑GTP loading to recruit mTORC1 to lysosomes; Arginine is sensed by

    Drugs: Arginine · L-Glutamine · Leucine · ATP · Magnesium cation · Zinc
    Enzymes: Cytosolic arginine sensor for mTORC1 subunit 1
  10. Drug

    Z-Val-Ala-Asp fluoromethyl ketone

    go.drugbank.com/drugs/DB07744
    Experimental

    It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.

    Categories: Compounds used in a research, industrial, or household setting