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Displaying results 5251 - 5260 of 10000 in total
  1. Drug

    G17DT Immunogen

    go.drugbank.com/drugs/DB04914
    Investigational

    G17DT Immunogen is a vaccine that neutralizes gastrin-17, a hormone required for the growth of a number of cancers of the gastrointestinal tract. … It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.

  2. Drug

    Stepronin

    go.drugbank.com/drugs/DB01423
    Experimental

    The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA. … Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Mixtures: LIDOCAINA E PRILOCAINA TEVA, LIDOCAINA E PRILOCAINA TEVASynonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, 2-(Propylamino)-o-propionotoluidide
  4. Drug

    Aluminium monostearate

    go.drugbank.com/drugs/DB01375
    Experimental

    Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. … Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2.

  5. Drug

    KAND567

    go.drugbank.com/drugs/DB16511
    Investigational

    KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation[L32908]. … Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as a treatment for those with the illness[L32908].

    Synonyms: 1-Pentanol, 2-[[2-aMino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyriMidin-7-yl]aMino]-4-Methyl-, (2R)-
  6. Drug

    Pimethixene

    go.drugbank.com/drugs/DB13292
    Approved

    Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring
  7. Drug

    Delapril

    go.drugbank.com/drugs/DB13312
    Investigational

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Rimiducid

    go.drugbank.com/drugs/DB04974
    Investigational

    Rimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. … [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness is currently under investigation.

  9. Drug

    IGN311

    go.drugbank.com/drugs/DB04988
    Experimental

    IGN311 is a humanized monoclonal antibody (mab) against the Lewis Y carbohydrate antigen, a blood-group-related oligosaccharide.

  10. Drug

    MLN0415

    go.drugbank.com/drugs/DB05183
    Experimental

    In preclinical studies, MLN0415 was shown to decrease NF-kB activation and down-regulate the expression of a number of inflammatory proteins. … Because inflammatory proteins play a critical role in inflammation and drive the inflammatory response to disease, controlling these proteins may prevent or slow disease progression.