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XMT-1001
go.drugbank.com/drugs/DB06069InvestigationalXMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. … XMT-1001 has demonstrated an improved therapeutic window as compared with CPT and irinotecan in human tumor xenografts models
Categories: Compounds used in a research, industrial, or household settingBafilomycin A1
go.drugbank.com/drugs/DB06733ExperimentalThe most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.
Synonyms: Bafilomycin A1Carbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnCarbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Categories: Compounds used in a research, industrial, or household settingBromfenac
go.drugbank.com/drugs/DB00963ApprovedWithdrawnBromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. … Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes.
Tiludronic acid
go.drugbank.com/drugs/DB01133ApprovedVet approvedWithdrawn[A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] … [A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.
Categories: Phospholipases A, antagonists & inhibitorsTiratricol
go.drugbank.com/drugs/DB03604ApprovedInvestigationalTiratricol is an analogue and active metabolite of the thyroid hormone triiodothyronine (T3). … [L53383] It was first approved by the EMA on February 12, 2025 for the treatment of peripheral thyrotoxicosis in patients with monocarboxylate transporter 8 (MCT8) deficiency,[A274038] a disorder characterized
Bos taurus gallstone
go.drugbank.com/drugs/DB14248InvestigationalBos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
D-Treitol
go.drugbank.com/drugs/DB03278ExperimentalA four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem]
OSI-930
go.drugbank.com/drugs/DB05913InvestigationalOSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2).
Human papillomavirus type 33 L1 capsid protein antigen
go.drugbank.com/drugs/DB10311ApprovedInvestigationalHuman papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33.