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Displaying results 5271 - 5280 of 7604 in total
  1. Drug

    ND1251

    go.drugbank.com/drugs/DB05132
    Experimental

    ND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression.

  2. Drug

    mRNA-3927

    go.drugbank.com/drugs/DB17669
    Investigational

    Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.[L45998]

  3. Drug

    Pimagedine

    go.drugbank.com/drugs/DB05383
    Investigational

    Pimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease.

  4. Drug

    Isatin

    go.drugbank.com/drugs/DB02095
    Experimental

    Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids.

  5. Drug

    Zaltoprofen

    go.drugbank.com/drugs/DB06737
    Investigational

    A non-steroidal anti-inflammatory drug approved for use in Japan in 1993.

    Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDS
  6. Drug

    Plozalizumab

    go.drugbank.com/drugs/DB12520
    Investigational

    The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis. … Preclinical studies suggest that CCR2 plays an important role in the trafficking of monocytes and macrophages to sites of inflammation.

  7. Drug

    Tasosartan

    go.drugbank.com/drugs/DB01349
    Experimental

    Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Quinestrol

    go.drugbank.com/drugs/DB04575
    Approved

    The 3-cyclopentyl ether of ethinyl estradiol.

  9. Drug

    Anecortave acetate

    go.drugbank.com/drugs/DB05288
    Investigational

    Anecortave acetate (Retaane) is an analog of cortisol acetate; among the modifications to the steroid are the removal of the 11ß hydroxyl OH group and an addition of a 21-acetate group.

  10. Drug

    Nalorphine

    go.drugbank.com/drugs/DB11490
    ExperimentalVet approved

    It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.