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Xanthine
go.drugbank.com/drugs/DB02134InvestigationalA purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xa...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesPlatelet Activating Factor
go.drugbank.com/drugs/DB02261ExperimentalCategories: P-glycoprotein inducers, P-glycoprotein substratesCytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid
go.drugbank.com/drugs/DB02485ExperimentalA nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein. [PubChem]
Synonyms: Cytidine-5'-Monophosphate-5-N-Acetylneuraminic AcidColforsin
go.drugbank.com/drugs/DB02587InvestigationalPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also...
Categories: P-glycoprotein inhibitorsStanolone
go.drugbank.com/drugs/DB02901IllicitInvestigationalA potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.
Categories: P-glycoprotein substratesOveporexton
go.drugbank.com/drugs/DB21680ApprovedOveporexton is an orally administered orexin receptor 2 (OX2R) agonist used to treat narcolepsy type 1 (NT1). NT1 is caused by the loss of orexin neuropeptide signaling, and oveporexton works by selectively activating OX2R to restore thi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMilsaperidone
go.drugbank.com/drugs/DB24348ApprovedInvestigationalMilsaperidone is an atypical antipsychotic agent that rapidly interconverts to iloperidone in vivo. Atypical antipsychotic agents work by blocking the D2 dopamine and serotonin receptor signalling pathways. Similarly, milsaperidone acts ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye -...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesCorticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedCorticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersTolevamer
go.drugbank.com/drugs/DB01344ApprovedSodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical ...
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